The Mobley Lab was established in 1984 in the Division of Infectious Diseases at The University of Maryland School of Medicine in Baltimore. The lab moved to The Department of Microbiology and Immunology at The University of Michigan Medical School in Ann Arbor, Michigan in the summer of 2004. The Mobley Lab is comprised of research professors, research technicians, undergraduates, graduate/doctoral students, and postdoctoral fellows dedicated to performing cutting edge research in the field of bacteriology. Since its inception, the lab has produced over 250 publications and trained more than 70 graduate students and postdoctoral fellows.

Mobley Lab, August 2018

-Molecular mechanisms of uropathogenesis

-Vaccine to prevent E. coli urinary tract infection

-E. coli virulence gene expression during clinical UTIs in women

-Virulence and fitness factors of Gram-negative bacteremia

Recent News and Announcements

June 2019: The Mobley lab attends ASM Microbe 2019 in San Francisco. Dr. Mark Anderson, Michael Breed, Aric Brown, Dr. Arwen Frick-Cheng, Dr. Sébastien Crépin, Valerie Forsyth, Stephanie Himpsl, Dr. Melanie Pearson, Christina Sarkissian Milner, Dr. Allyson Shea, Sara Smith, and Danelle Weakland present posters. Danelle presents a symposium talk, Michael and Aric have rapid fire presentations, and Allyson gives an additional poster talk. Danelle and Allyson also received ASM travel awards, and Aric received a conference travel grant from the University of Michigan Rackham Graduate School. This is the 35th ASM General Meeting/Microbe the lab has attended as a group.

June 2019: "Flexible metabolism and suppression of latent enzymes are important for E. coli adaptation to diverse environments within the host" is published in Journal of Bacteriology.

May 2019: Congratulations to Madison Fitzgerald for being accepted into the Michigan Predoctoral Training Program in Genetics! This is one of the oldest NIH supported training programs and provides financial support as well as a rigorous curriculum, interactive seminars, and an annual retreat.

May 2019: Congratulations to Dr. Laura Mike on receiving a K22 Career Transition Award from the National Institute of Allergy and Infectious Diseases!

May 2019: Lab manager and research technician Stephanie Himpsl has been selected to receive an Endowment for the Basic Sciences Research Staff Award, which is given in recognition of outstanding research productivity and innovation over the past year at the University of Michigan Medical School. Stephanie is an outstanding scientist serving as co-author on 16 papers, including two as first author and three as co-first author. She has been a contributing author or presenting author on 22 national meeting abstracts. Congratulations!

April 2019: Madison Fitzgerald joins the lab as a Ph.D. Student. Welcome!

April 2019: "Twin arginine translocation, ammonia incorporation, and polyamine biosynthesis are crucial for Proteus mirabilis fitness during bloodstream infection" is published in PLoS Pathogens.

March 2019: Dr. Mobley finished his 6th and final lecture as an ASM Distinguished Lecturer in Baltimore.

February 2019: Dr. Sapna Pahil joins the lab as a Postdoctoral Fellow. Welcome!

February 2019: Congratulations to Lindsay Mitchell, M.S. on accepting a position at Pfizer in Cambridge, Massachusetts!